منابع مشابه
Choice and Design of Adjuvants for Parenteral and Mucosal Vaccines
The existence of pathogens that escape recognition by specific vaccines, the need to improve existing vaccines and the increased availability of therapeutic (non-infectious disease) vaccines necessitate the rational development of novel vaccine concepts based on the induction of protective cell-mediated immune responses. For naive T-cell activation, several signals resulting from innate and ada...
متن کاملPotential of polymeric particles as future vaccine delivery systems/adjuvants for parenteral and non-parenteral immunization against tuberculosis: A systematic review
Objective(s): Production of effective tuberculosis (TB) vaccine is necessity. However, the development of new subunit vaccines is faced with concerns about their weak immunogenicity. To overcome such problems, polymers-based vaccine delivery systems have been proposed to be used via various routes. The purpose of this study was to determine the potential of polymeric particles as future vaccine...
متن کاملA Comparative Study of Protective Immunity Provided by Oral, Intranasal and Parenteral Canine Bordetella bronchiseptica Vaccines
The present study was designed to determine if an oral live Bordetella bronchiseptica vaccine protects dogs from developing signs of respiratory disease after challenge with virulent Bordetella bronchiseptica. The study was also designed to compare the level of protection induced by the oral vaccine with the protection provided by an intranasal live vaccine and an injected killed vaccine. Forty...
متن کاملNon-specific effects of childhood vaccines
Non-specific effects of vaccines or “off target effects” as they are sometimes called can be defined as effects of a vaccine beyond their intended target pathogen or disease. These effects can be beneficial as well as harmful. The published evidence on non-specific effects of childhood vaccines remain confusing, so the linked systematic reviews by Higgins and colleagues (doi:10.1136/bmj.i5170) ...
متن کاملVaccines in Non-Small Cell Lung Cancer
Immunotherapy as an option of treatment in cancer has experienced an important development with the inclusion of vaccines. In lung cancer this type of treatment has emerged and vaccines can be classified in three groups: antigen-specific vaccines, tumor cell vaccines, and dendritic cell vaccines. Emepepimut (L-BLP25) and MAGE-A3 have been the vaccines most widely studied. Their promising result...
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ژورنال
عنوان ژورنال: BMJ
سال: 2004
ISSN: 0959-8138,1468-5833
DOI: 10.1136/bmj.329.7457.62